HPV Vaccine Needs To Reach Boys Too
HPV疫苗应同样用于男性
Gypsyamber D’Souza of Johns Hopkins University discussed the rise in HPV-related oral cancer, its connection to oral sex and the risk for men at the annual meeting of the American Association for the Advancement of Science.
约翰·霍普斯金大学(Johns Hopkins University)的吉氏安博·迪索扎(Gypsyamber D’Souza)在美国科学技术发展协会(American Association for the Advancement of Science)的年度会议上讨论HPV(人类乳头瘤病毒)相关的口腔癌患者增长现象，其与口交性行为的关系，以及男性患病的风险。

撰文/播音 史蒂夫·米尔斯基(Steve Mirsky)
翻译 Meatle
审校 乔虹

 “Human papillomavirus, or HPV, now causes the majority of tonsillar cancers in the United States and many western nations. And the risk of these cancers has been increasing.”

“人类乳头瘤病毒(human papillomavirus)，或HPV，在现今的包括美国在内的西方国家中是扁桃体癌的主要成因。人们患上这种癌症的风险在连年上升。”

Gypsyamber D’Souza of Johns Hopkins University, February 12th at the annual meeting of the American Association for the Advancement of Science in Washington, DC.
约翰?霍普斯金大学(Johns Hopkins University)的吉氏安博?迪索扎(Gypsyamber D’Souza)在2月12日举行于华盛顿DC举行的美国科学技术发展协会(American Association for the Advancement of Science)的年度会议上发表演说。

“And it’s much higher in men than in women…we know performing oral sex is the main risk factor for oral HPV infection. And our research shows that performing oral sex is more common in younger generations than in previous generations. And that people are not only more likely to have performed oral sex but with more partners and to initiate it at any earlier age. And all of these differences in sexual behavior across age cohorts or generations do explain the differences that we see in oral HPV prevalence and in HPV-related oropharyngeal cancer across the generations and why the rate of this cancer is increasing...
“男性的患病风险显著的高于女性…我们知道进行口交是HPV口部感染的主要原因。我们的研究表明，相对于以往的人们，口交在年轻一代中更为常见。这些年轻人不仅仅更有可能进行口交，他们还倾向于与更多的伴侣、在更早的年龄开始这种行为。而这些年龄与时代的差异解释了我们所发现的HPV蔓延与HPV相关的口咽癌在各个年龄层的差异及发病数上升的原因…”

“But differences in sexual behavior do not explain the differences that we see between men and women in oral HPV infection and HPV-related cancer…
“但性行为的差异并没有解释到我们所观察到的男女之间的口腔HPV感染与HPV相关癌症的数量的差异…”

“Men are not only more likely to become infected with oral HPV infection than women, but our research also showed that once you become infected, men are less likely to clear these infections than women. Further contributing to their cancer risk.”
“相对女性，男性不单单更有可能遭遇口腔HPV感染，而且我们的研究展现了男性更难清除HPV感染。这进一步增加了他们患上癌症的风险。”

Which means that it’s not just girls and women who should get the HPV vaccine.
这意味着不单单是女孩或是妇女需要进行HPV疫苗接种。

“In terms of vaccination of boys, as a researcher who sees the patients with these cancers, the fact that there is a vaccine with great potential to prevent them is very compelling. Our vaccination rates have lagged in boys severely in the States, which is disappointing, but there is a lot of effort to improving that. And I think it’s quite an urgent public health issue to increase HPV vaccination in boys as well as girls.”
“作为看望过这些癌症病人的研究者，在男性接种疫苗的方面，我们注意到已经有一种有很大潜在效果的疫苗。在美国，男孩接种这种疫苗的数量相较于女性大为落后，这令我们失望，然而我们有很多方法能扭转这种状况。提高HPV的疫苗在男性和女性之中的接种率，我认为这是一个颇为重要的公共健康问题。